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Benzene: The Chemical and its Side Effects 
 
by Kealoha Wells August 01, 2005

What is Benzene?

Benzene is a widely used chemical formed from both natural resources (volcanoes and forest fires) and human activities. It is a highly flammable colorless liquid that evaporates quickly. Relatively soluble in water, it can be mixed with some polar solvents (alcohol, chloroform, and carbon tetrachloride) without separating into two phases.

Its chemical formula is C6H6 and it is made up of 92.3%carbon and 7.7% hydrogen. The Benzene molecule is represented by six sets of carbon and hydrogen atoms connected as a hexagon and held together with alternating single and double bonds.Its chemical and physical properties are as follow:

Molecular Weight 78.11 g/moleMelting Point 5.5 degrees CelsiusBoiling Point 80.1 degrees CelsiusDensity at 20 degrees Celsius 0.879 g/mlVapor Pressure at 25 degrees Celsius 0.13 atm.Flash Point (closed cup) -11.1 degrees Celsius Solubility in Water at 25 degrees Celsius 1.8 g/LConversions at 25 degrees Celsius 1 ppm = 3.25 mg/m31 mg/liter = 313 ppm

ppm = part per million

Is it Dangerous?

In the 1980’s, benzene replaced lead in gasoline, when the latter was proven to be toxic. Unfortunately, the trade off turned out to be merely one poisonous substance for another.

Benzene has been confirmed as a human carcinogen (cancer-causing agent) by the International Agency for Research on Cancer, the Department of Health and Human Services (DHHS), and the Environmental Protection Agency (EPA).

Is it Regulated?

The EPA requires that spills or accidental releases into the environment of 10 pounds or more of benzene be reported to the EPA. The EPA has set the maximum permissible level of benzene in drinking water at 0.005 milligrams per liter (0.005 mg/L).

The Occupational Safety and Health Administration (OSHA) has set an exposure limit of 1 part of benzene per million parts of air (1ppm) in the workplace during an 8-hour workday in a 40-hour workweek, with a short term exposure of limit of 5ppm. Long term exposure has been shown to affect bone marrow and cause serious and life-threatening health conditions.

What are its Uses and Side Effects?

While benzene as a solvent has been banned for more than two decades, it is still used to make other chemicals and exposure to the toxic substance is still rampant. It is used to make the chemicals used in the production of nylons, plastics, lubricants, dyes, resins, synthetic fibers, detergents, drugs, pesticides, and rubber. Benzene is also a natural part of crude oil and cigarette smoke.

The average person is exposed to possible benzene poisoning both inside and outside the home. Inside hazards include glues, paints, detergents, and furniture wax. Outside hazards include the air around automobile service stations, industrial emissions, and motor vehicle exhaust. Of course, many people are exposed to cigarette smoke both inside, outside, or both.

Effects of benzene poisoning by breathing it in include drowsiness, dizziness, unconsciousness, accelerated heart rate, headaches, and tremors. Some women who breathed high levels of benzene for many months had irregular menstrual periods and a decrease in the size of their ovaries. And while it is not known whether benzene exposure affects the developing fetus in pregnant women, animal studies have shown low birth weights, delayed bone formation, and bone marrow damage when pregnant animals breathed benzene. The effects on the fertility of men are still unknown.

Benzene in the air can attach to rain or snow and be carried back down to the ground. It breaks down slowly in water and soil, and can pass through the soil into underground water. Leakage from hazardous waste sites and faulty pipes can also result in contaminated drinking water. Benzene ingested orally causes vomiting, stomach irritation, dizziness, sleepiness, convulsions, accelerated heart rate, and death.

Deaths caused by benzene have been attributed to asphyxiation, respiratory arrest, and CNS (central nervous system) depression. Autopsies have also shown lung hemorrhages, cerebral edema, and congestion.

Cancer cases have been associated with people exposed to benzene for less than five years to more than thirty years. Benzene has been linked to multiple leukemia cases, usually acute myelogenous leukemia (AML), but also chronic myelogenous leukemia (CML), acute lymphocytic leukemia (ALL), chronic lymphohcytic leukemia (CLL), and Hairy-Cell Leukemia (HCL). It has also been associated with multiple myeloma, non-Hodgkin’s lymphoma, myelodyplastic syndrome, myelodysplasia, and secondary aplastic anemia. These diseases are a result of the chronic damage done to the body’s bone marrow.

More than 300,000 people per year are exposed to the chemical through their workplace, and over 10,000 deaths per year are attributed to benzene exposure in the United States alone. People working with petroleum products are exposed to significant amounts of benzene.

The following jobs fall under the high risk category.

  • Painters
  • Adhesive Production Workers
  • Chemical Workers
  • Dock Workers
  • Paper and Pulp Production Workers
  • Pipe Fitters
  • Barge Workers
  • Offshore Workers
  • Refinery Workers
  • Gas Station Attendants
  • Pesticide Manufacturers
  • Industrial Plant Workers (using solvents)
  • Rubber Workers
  • Shoe/Leather Workers
  • Truck Drivers

Can I Be Tested?

There are breath and blood tests available for determining the presence of benzene in a person; unfortunately, they are only accurate for recent exposure. There is also a urine test but it works on a slightly different premise. Benzene converts to metabolites in the body and some of them can be measured by urinalysis. This too is only accurate for recent exposure.

What about Workplace Precautions?

Wear solvent-resistant gloves and clothing as benzene can be absorbed through the skin. Neoprene, Silver Shield, Polyvinyl Alcohol and Butyl Neoprene are often recommended as protective materials, but contact manufacturers and safety equipment suppliers for recommendations on the glove/clothing material that offers the most protection in your daily exposure. Keep all protective clothing clean and put them on every day before arriving at work. Wash thoroughly at the end of the work shift and immediately after any exposure to benzene.

Do not wear contact lenses when working with benzene; do wear impact and splash resistant goggles when working with liquids. If you work with corrosive, highly irritating, or toxic substances, wear a face shield along with the goggles.

Where the potential exists for exposure over the 1ppm standard, a supplied-air respirator with a full face piece operated in a positive-pressure mode. Improper use of respirators is dangerous and should only be used according to a written program as described in OSHA 1910.34.

Workplaces should have a regulated, marked area where all benzene is handled, used, or stored. Hazard and warning information should be posted in plain view, and potentially exposed workers should receive training and education on the health and safety hazards of working with benzene.

Is There Any Legal Recourse?

Under the law, victims of benzene-related health effects may be eligible for compensation. A simple internet search will produce multiple class-action suits as well as attorneys and organizations that stand ready to assist you. If you think you have been harmed by benzene exposure, you may want to consider seeking consultation to learn more about your options.


 




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