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Drug Interactions With Three Commonly Used Over-the-Counter Pain Medications 
 
by Robbi Erickson August 18, 2005

Ibuprofen

Ibuprofen is used for pain management. It should be noted that severe allergic reactions can occur with the use of Ibuprofen, so if you have had an allergic reaction to any other pain medication you should ask your doctor before taking a product with Ibuprofen in it. Warning signs for an allergic reaction to Ibuprofen included blurred vision and changes in color vision. If you have a cardiac condition, Ibuprofen may also increase your chances of edema and water retention. Ibuprofen also impacts a person’s ability to clot, and therefore if you have any type of bleeding problem such as ulcerations or lesions, Ibuprofen should not be taken unless specified by your doctor. Women who are pregnant should also not use Ibuprofen during their last trimester as it may impair the development of their baby. In addition to these warnings, Ibuprofen also has a tendency to interact with the following drug:

1. Baclofen

Baclofen, used as a muscle relaxant an antispastic agent, could lead to baclofen toxicity problems.

General Precautions

If you take any of these drugs, consult your doctor for the proper dosages and the proper selection of over-the counter pain medications. Your doctor will be able to recommend the correct type of medication for your situation

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